JEE Main 2023 — Biomolecules Question with Solution
From: JEE Main 2023 (Online) 10th April Morning Shift
Question
The one that does not stabilize 2 and 3 structures of proteins is
Choose an option
Show full solutionCorrect option: A
Step-by-step explanation
The stabilization of secondary (2°) and tertiary (3°) structures of proteins mainly involves interactions such as disulfide bridges (S-S linkages), van der Waals forces, hydrogen bonding, and hydrophobic interactions.
Option A: O-O linkage is not usually involved in the stabilization of protein structures. Oxygen-oxygen single bonds are generally unstable and rarely observed in nature.
Option B: S-S linkage (disulfide bridges) between cysteine residues in a protein can help stabilize the protein's structure, particularly its tertiary structure.
Option C: Van der Waals forces can contribute to the stabilization of protein structures, particularly in the interior of the protein where they can promote hydrophobic interactions.
Option D: Hydrogen bonding can play a critical role in the formation and stabilization of secondary structures such as alpha-helices and beta-sheets.
Therefore, the correct answer is Option A (-O-O- linkage).
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This is a previous-year question from JEE Main 2023, covering the Biomolecules chapter of Chemistry. PrepSharp catalogues every PYQ from JEE Main with a verified answer key and step-by-step solution prepared by IIT alumni — so you can search by chapter, topic or year and revise efficiently.